72 Hours in San Francisco – A Local’s Guide to the City

San Francisco. Home of the Golden Gate Bridge, the classic cable car, Fisherman’s Wharf, steep and windy hills, Alcatraz, the Giants. 72 Hours in San Francisco can fly by with so much to do!

weekend guide to San Francisco

72 Hours in San Francisco

It’s a beloved city that earns its reputation as one of America’s best, and millions travel every year to experience these iconic tourist thrills.

And truly, they’re all pretty damn great. But as someone who lives in the Bay Area, full time, Trip Advisor’s top attractions for San Francisco simply fall flat.


Plan Your San Francisco Vacation

Get Your Guide - A great site for booking tours and for finding discounts

Lonely Planet San Francisco Guide - We use Lonely Planet travel guides whenever we travel.

Hop on Hop Off Bus - When we went to San Francisco, we used the Hop on Hop  Off Bus to see all the highlights and get around the city. San Francisco seemed quite spread out to us, so this was an excellent way to see it all.

Rent The Rock to get in the mood for Alcatraz and San Francisco with Nicholas Cage and Sean Connery

Mrs Doubtfire -  Or for a more family friendly movie, check out Robbin Williams at his best in Mrs. Doubtfire showcasing the beautiful city.

Golden Gate Bay Cruise - You have got to get on the water in San Francisco, see Alcatraz and the Golden Gate Bridge on this Bay Cruise.

I Left My Heart in San Francisco - Get Tony Bennett's famous love song to the city.

Alcatraz Ticket & Guided Bicycle Tour - Not only do you visit Alcatraz Island, you also get a guided bike tour of San Francisco's famous piers, Palace of Fine Arts and a cycle across the Golden Gate Bridge.

Of course, check out the bridge, head to Lombard Street, do whatever you need to do to feel good about your tourism intake, but if you’re really looking for an experience that reveals the fun, the quirk, and the culture of this amazingly diverse city, ditch the guide books, and listen up.

You’ll never have enough time to soak up everything the city has to offer, but this weekend guide to the city will fill a full 72 hours in San Francisco and take you to some of the city’s best areas, where you’ll find less tourists, and more awesome.
san francisco travel guide

Suggested San Francisco Hotels

72 hours in San Francisco

Ritz Carlton

Located between Union Square and China Town. 5 Star Service, Spa, Business & Leisure

Check out Availability & Prices

Trip Advisor / Booking.com


72 hours in San Francisco

Palace Hotel

The city's most historic grand hotel with contemporary luxury rooms. Famous for afternoon tea.

Check out Availability & Prices

Trip Advisor / Booking.com

Getting around and where to stay in San Francisco

First things first:
Get the Uber App. This is the best way to get around San Francisco, and don’t be afraid to use UberPool (it’s carpool option) — it’s cheaper and totally safe. Plus, you’ll meet more locals this way.

Check in…on Airbnb. Most of San Francisco’s hotel options are all congregated around the central Union Square/Fisherman’s Wharf area, and while there are some decent options (The Fairmont is classic if you’re rolling high), why not use one of the Bay Area Tech scene’s pride-and-joys? Not all areas are great for tourists, so stick to Nob/Russian Hill, Castro/Duboce Triangle.

Download this Google Map. It’s got all the locales you’ll need for your weekend.

san francisco travel guide

Got 72 Hours in San Francisco? 

Your weekend guide to San Francisco

Okay, let’s get started.

Friday evening:

Head over to North Beach to get a feel for classic San Francisco. Like the rest of the city, the hipsters have started to make their mark on this neighborhood, but you can still catch glimpses of what the city was like during it’s Beat-poetry days.

Wander through City Lights bookshop, have a drink at Vesuvio, and finish with dinner at The House (reservations recommended)  — an old-establishment Asian fusion restaurant that isn’t trying to prove itself, because quite simply, it doesn’t need to. Order the seafood, and prepare to have your mind blown.

Finish with a nightcap at 15 Romolo, where you’ll experience San Francisco’s A+ cocktail scene.

More San Francisco Hotels


where to stay in San Francisco

Hotel Drisco

Excellent location close to main attractions, 5 star service. Breakfast, wine & hors d'oeuvres included

Check out Availability & Prices

Trip Advisor / Booking.com


72 hours in San Francisco

Four Seasons

You can't go wrong with Fours Seasons, 5 Star hotel and Service, great for couples.
Downside: no pool on site

Check out Availability & Prices

Trip Advisor / Booking.com


Saturday morning:

Get up early and go to the iconic Ferry Building to take in one of the city’s best farmer’s markets, and a hallmark of San Francisco’s organic food scene.

Restaurants and food trucks will have stands with mouth-watering breakfast treats (the 4505 breakfast sandwich is sinfully delicious) and don’t forget to grab a cup of Blue Bottle Coffee in the Ferry Building itself.

The craft with which they pour your cup will prove pretentious — but damn, is it worth it.

Enjoy every sip as you watch the boats pass under the area’s overshadowed — but also impressive — Bay Bridge.

72 hours in San Francisco

San Francisco Bay Bridge

Saturday afternoon:

Take the F-train (a street car that resembles a cable car, but with less tourists) from the Ferry Building down Market Street, until it ends on Castro Street.

Walk down Castro street and enjoy the colors, the rainbow crosswalks, and the energy of one of America’s first and proudest gay neighborhoods.

Consider yourself lucky if you get to see a few (almost) naked gentlemen on an afternoon stroll. This is the real San Francisco.

san francisco travel guides

Take a left on 17th Street, and if you’re feeling tired, dip into Philz coffee and get a Mint Mojito Iced Coffee.

Once re-fueled, make your way to Valencia Street, where you’ll find San Francisco’s comprehensive hipster scene in the form of coffee shops, thrift stores, and of course, people.

The boutiques in this area are as impressive in decor as they are in goods, so enjoy the art and the shopping all at once.

Make sure you check out stores like The Community Thrift Store, Thread Lounge, 826 Valencia (founded by Dave Eggers), and Paxton Gate to get a full breadth of this diverse and oh-so-trendy neighborhood.

Once your appetite picks up, get a Delfina pizza to go and stop by Bi-Rite for some ice cream before picking a spot to picnic in Dolores Park, where you’ll find a sea of people basking in sun…or fog, whichever Karl has decided to deliver that day.

Watch the night fall on the city, and don’t be afraid to try the many treats hawked by savvy entrepreneurs who wander the park (The ‘Hey, Cookie!’ lady is an all-time fave).

Read about outdoor adventures and hiking in San Francisco.

San Francisco's Dolores Park

San Francisco Travel Guide


Saturday evening:

Once you’re done with your picnic, head back to Valencia street for happy hour at Blondie’s, an old watering hole famous for their giant martinis.

After one drink (that’s all you’ll need), mosey on over to Mission Street.

Your goal is to have a meal at Mission Chinese — the mouth-watering-and-mouth-numbing restaurant that serves modern Sichuan Chinese food. Prepare for spice.

But, if the line is too long, or you can’t handle the spice, walk across the street to Gracias Madre, a vegan Mexican restaurant that will make you forget that there’s no meat.

Learn more about visiting California with this guide to the Big Sur Coastal Drive.

Saturday night:

To work off all the food and booze you just consumed, it’s time to get a little exercise…in the form of roller-skating.

The Church of 8 Wheels, a Burning Man Camp turned local institution, hosts roller-skate-parties every Saturday night (and Friday) until 11 pm. It’s the most fun you’ve had since the last time you roller-skated, which was likely in 3rd grade.

san francisco travel guide

Roller Skating in San Francisco

Saturday late-night:

After roller-skating, if you’re still awake, take a quick Uber to Smuggler’s Cove, the pirate-themed bar famous for their rum cocktails.

They’ve blacked our their windows so you can enjoy the over-the-top (in a good way) decor while sipping on the finest of tiki creations. They serve all-types of alcohol, but let them impress you with their rum.

Sunday morning:

Enjoy a lazy morning and grab an easy bite at Flour & Co., a tiny bakery in Nob Hill that serves unbelievable breakfast and coffee, including gluten-free bread that tastes even better than the gluten-ed kind.

Everything on their menu is delicious, but they’re breakfast sandwich is the stuff dreams are made of.

Check out these beaches in California you've never heard of.


Sunday day:

Take an Uber to Golden Gate Park and either rent a bike or walk around the museum plaza.

The Aids Memorial Grove is especially beautiful, and make sure you end your time in the (free!) observation deck of the deYoung Museum.

If it’s a clear day, it’s one of the best views of the city, and if you do want to see some great art, the deYoung is a fantastic option.

San Francisco Travel guide

deYoung Museum

Finish your epic weekend in San Francisco by strolling over to Haight Ashbury — a touristy, but iconic part of the city’s hippie counterculture days — now full of costume and thrift shops. For record collectors, Amoeba Music is a must.

And as final cap to your time in San Francisco, end with one of the city’s signature burritos from Street Taco. Yum.

San Francisco Travel Guide

San Francisco at Dusk

You should be full and exhausted by now, so it’s time to go home.

Author bio: Postcards from Yonder

san francisco travel guide


Kevin and Katie are two artists behind the creative travel blog, Postcards From Yonder. You can follow them on Instagram and sign up for a real postcard.

Read next: The Ultimate San Francisco Photography Guide

Sharing is caring!

Join the Conversation

12 Responses to "72 Hours in San Francisco – A Local’s Guide to the City"

Join the Conversation

Your email address will not be published. Required fields are marked *